This is possible if you use Smart Bridge PRO to integrate your Serena shades. Smart bridge non-pro will not work. You'll want C4 keypads if you want to integrate multiple shade/light scenes. If you want a bit more cost effective route to control shades only (full open/full close, raise/lower, one favorite position for group or single shade), you can use wall/pedestal mounted pico (PJ2-3BRL-GWH-S01 available in different colors). I think you'll be happy with Serenas. I have them installed throughout the house and it's never skip a beat. Also, the only difference after talking with Lutron suppor